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现在位置:首页 > 杭海英研究组 > 发表论文
发表的论文论著
 

   2019 

  An L, Li YM, Fan YJ, He N, Ran FL, Qu HZ, Wang YQ, Zhao XT, Ye C, Jiang YD, Fang X*, Hang HY*. The Trends in Global Gene Expression in Mouse Embryonic Stem Cells During Spaceflight. Frontiers in Genetics. 2019 Sep.

  Wang J, An L, Zhao Y, Zhang C, Li S, Ye C, Jing S, Hang H*. In vitro affinity maturation of antibody against membrane-bound GPCR molecules. Appl Microbiol Biotechnol. 2019 Sep;103(18):7703-7717.

   2018 

  Chen C, Wang J, Zhao Y, Chen SP, Hu ZS, Chen L*, Hang HY*. Enhancers improve the AID induced hypermutation in episomal vector for antibody affinity maturation in mammalian cell display. Antibodies. 2018,7,42.

  Fan YJ, Liu YH, Wang YL, Kong BJ, Zhao Y, Ye C, An LL*, Hang HY*. Interaction of the checkpoint protein Rad9 and the non-homologous end-joining protein Ku70. Progress in Biochemistry and Biophysics. 2018, 45(10):1054-1067. 

  Hu ZS, Ye C, Mi W, Zhao Y, Quan C, Li WW*, Li HM*, Hang HY*. Light-scattering detection within the difficult size range of protein particle measurement using flow cytometry. Nanoscale. 2018 Nov 7;10(41):19277-19285. 

  Kong BJ, Cao Y, Wu DN, An LL, Ran FL, Lin Y, Ye C, Wang HL*, Hang HY*. Affinity maturation of an antibody for the UV-induced DNA lesions 6,4 pyrimidine-pyrimidones. Applied Microbiology and Biotechnology. 2018 Aug;102(15):6409-6424.

   2016 

  Sun S, Yang X, Wang H, Zhao Y, Lin Y, Ye C, Fang X, Hang H*. Antibody affinity maturation through combining display of two-chain paired antibody and precision flow cytometric sorting. Appl Microbiol Biotechnol. 2016 Jul;100(13):5977-88. 

  Chen C, Li N, Zhao Y*, Hang H*. Coupling Recombinase-mediated cassette exchange with somatic hypermutation for antibody affinity maturation in CHO cells. Biotechnology & Bioengineering. 2016 Jan;113(1):39-51. 

  2015 

  Zhao Y, Ma X, Wang J, Chen S, Yuan H, Xu A, Hang H*, Wu L. The Roles of p21(Waf1/CIP1) and Hus1 in Generation and Transmission of Damage Signals Stimulated by Low-Dose Alpha-Particle Irradiation. Radiat Res. 2015 Dec;184(6):578-85. 

  Li N, An L, Hang H*. Increased Sensitivity of DNA Damage Response-Deficient Cells to Stimulated Microgravity-Induced DNA Lesions. PLOS ONE. 2015, 10(4):e0125236. 

  Zhang Z, Cai Z, Li K, Fang Y, An L, Hu Z*, Wang S*, Hang H*. The Effect of lonizing Radiation on mRNA Levels of the DNA Damage Response Genes Rad9, Rad1 and Hus1 in Various Mouse Tissues. Radiation Research. 2015,183:94-104. 

  2014年   

  刘春春,赵云,杭海英. 流式细胞术揭示出枯草芽孢杆菌多态异质性. 生物化学与生物物理进展. 2014,41(4):393-402.   

  Yue H, Zhao Y, Hang H*. Improvement of engineered microbial production of alkanes through a dual-reporter screening system. 生物物理学报. 2014, 30(6):424-432..   

  2013年   

  Yang X, Sun S, Wang HF, Hang H*. Comparison of autotransporter and ice nucleation protein as carrier proteins for antibody display on the cell surface of Escherichia coli. Prog Biochem Biophys. 2013,40(12):1209-1219.   

  Li T, Wang Z, Zhao Y, He W, An L, Liu S, Liu Y, Wang H, Hang H*. Checkpoint protein Rad9 plays an important role in nucleotide excision repair. DNA Repair. 2013 Apr 1;12(4):284-92.   

  2012年   

  Chen S , Qiu J, Chen C, Liu C, Liu Y, An L, Jia J, Tang J, Wu L, Hang H*. Affinity maturation of anti-TNF-α scFv with somatic hypermutation in non-B cells. Protein and Cell. 2012 Jun;3(6):460-9.   

  Zhao Y, He W, Liu WF, Liu CC, Feng LK, Sun L, Yan YB, Hang HY*. Two distinct states of Escherichia coli cells that overexpress the recombinant heterogeneous β-galactosidase. J Biol Chem. 2012 Mar 16;287(12):9259-68.

  2011年   

  Wang Y, An L, Jiang Y, Hang H*. Effects of Simulated Microgravity on Embryonic Stem Cells. PLoS One. 2011;6(12):e29214.   

  Zhang C, Liu Y, Hu Z, An L, He Y, Hang H*. Targeted deletion of mouse Rad1 leads to deficient cellular DNA damage responses. Protein Cell. 2011 May;2(5):410-22.   

  He W, Ma X, Yang X, Zhao Y, Qiu J, Hang H*. A role for the arginine methylation of Rad9 in checkpoint control and cellular sensitivity to DNA damage. Nucleic Acids Res. 2011 Jun;39(11):4719-27.   

  2010年   

  An L, Wang Y, Liu Y, Yang X, Liu C, Hu Z, He W, Song W and Hang H*. Rad9 is required for B cell proliferation and immunoglobulin class switch recombination. J Biol Chem. 2010 Nov 12;285(46):35267-73.   

  Qiu J, Jung ST, Georgiou G, Hang HY*. Enrichment of Escherichia coli Spheroplasts Displaying scFv Antibodies specific for antigens expressed on the human cell surface. Appl Microbiol Biotechnol. 2010 Dec;88(6):1385-91.   

  Cui P, Lin Q, Xin C, Han L, An L, Wang Y, Hu Z, Ding F, Zhang L, Hu S*, Hang H*, Yu J*. Hydroxyurea-induced Global Transcriptional Suppression in Mouse ES Cells. Carcinogenesis. 2010 31(9):1661-8.

  Han L, Hu Z, Liu Y, Wang X, Hopkins KM, Lieberman HB, Hang H*. Mouse Rad1 deletion enhances susceptibility for skin tumor development. Mol Cancer. 2010 Mar 24;9:67   

  2009年   

  Xu M, Bai L, Gong Y, Xie W, Hang H*, Jiang T. Structure and functional implications of the human rad9-hus1-rad1 cell cycle checkpoint complex. J Biol Chem. 2009 Jul 31;284(31):20457-61.   

  Cui Z, Chen X, Lu B, Park SK, Xu T, Xie Z, Xue P, Hou J, Hang H, Yates JR 3rd, Yang F. Preliminary quantitative profile of differential protein expression between rat L6 myoblasts and myotubes by stable isotope labeling with amino acids in cell culture. Proteomics. 9:1274-92, 2009.

  2008年   

  He W, Zhao Y, Zhang C, An L, Hu Z, Liu Y, Han L, Bi L, Xie Z, Xue P, Yang F, Hang H*. Rad9 plays an important role in DNA mismatch repair through physical interaction with MLH1. Nucleic Acids Res. 36:6406-17 (2008).  

  Zhang C, Zhang CX, He Y and Hang H*. Phosphorylation Sites on Tyr28 and the C-terminus of Rad9 are Required for Inhibition of Premature Chromosomal Condensation Across the Entire S Phase. Cell Physiol Biochem, 22:295-306, 2008.   

  Hu Z, Liu Y, Zhang C, Zhao Y, He W, Han L, Yang L, Hopkins KM, Yang X, Lieberman HB, Hang H*. Targeted deletion of Rad9 in mouse skin keratinocytes enhances genotoxin-induced tumor development. Cancer Res. 68:5552-61,2008.   

  Guo Z, Chavez V, Singh P, Finger LD, Hang H, Hegde ML, Shen B. Comprehensive mapping of the C-terminus of flap endonuclease-1 reveals distinct interaction sites for five proteins that represent different DNA replication and repair pathways. J Mol Biol. 377:679-90, 2008.   

  Wang S, Tang M, Pei B, Xiao X, Wang J, Hang H, Wu L. Cadmium-induced germline apoptosis in Caenorhabditis elegans: the roles of HUS1, p53, and MAPK signaling pathways. Toxicol Sci. 102:345-51, 2008.   

  Pei B, Wang S, Guo X, Wang J, Yang G, Hang H, Wu L. Arsenite-induced germline apoptosis through a MAPK-dependent, p53-independent pathway in Caenorhabditis elegans. Chem Res Toxicol. 21:1530-5, 2008   

  Yuan C, Jiao L, Yang L, Ying W, Hu Z, Liu J, Cui F, Li L, Qian L, Teng Y, Hang H, Qian X, Yang X. The up-regulation of 14-3-3 proteins in Smad4 deficient epidermis and hair follicles at catagen. Proteomics. 8:2230-43, 2008.

  2007年   

  Ning Tang, Gangjun Du, Nan Wang, Chunchun Liu, Haiying Hang*, Wei Liang*. Improving Penetration in Tumors with Nano-assemblies of Phospholipids and Doxorubicin. J Natl Cancer Inst. . 2007 Jul 4;99(13):1004-15.   

  2006年   

  刘春春 杭海英*. 生物大分子相互作用检测技术新进展———三色荧光级联荧光共振能量转移技术. 生物化学与生物物理进展. 33:292-296, 2006.   

  苏华 杭海英*. 生理条件下的S期检查点. 生物化学与生物物理进展. 33:122-126, 2006.   

  2004年   

  Hopkins KM, Auerbach W, Wang XY, Hande MP, Hang H, Wolgemuth DJ, Joyner AL, Lieberman HB. Deletion of mouse rad9 causes abnormal cellular responses to DNA damage, genomic instability, and embryonic lethality. Mol Cell Biol. 24:7235-48, 2004.   

  Hopkins KM, Wang X, Berlin A, Hang H, Thaker HM, Lieberman HB. Expression of mammalian paralogues of HRAD9 and Mrad9 checkpoint control genes in normal and cancerous testicular tissue. Cancer Res. 63:5291-8, 2003.   

  Hang H* and Fox MH. Analysis of the mammalian cell cycle by flow cytometry. In Cell Cycle Checkpoint Control Protocols, (Lieberman HB, eds), Humana Press, Totowa, NJ, 2004.   

  2002年   

  Hang H*, Zhang Y, Dunbrack RL, Jr, Wang C, and Lieberman HB. Identification and Characterization of a Paralogue of Human Cell Cycle Checkpoint Gene HUS1. Genomics. 79:487-92, 2002.   

  2000年   

  Komatsu K, Wharton W, Hang H, Wu C, Singh S, Lieberman HB, Pledger WJ, Wang HG. PCNA interacts with hHus1/hRad9 in response to DNA damage and replication inhibition. Oncogene. 19:5291-7, 2000.   

  H. Hang, and H.B. Lieberman. Physical interactions among human checkpoint proteins HUS1p, RAD1p, and RAD9p, and implications for the regulation of cell cycle progression. Genomics 65:24-33, 2000.   

  Komatsu K, Miyashita T, Hang H, Hopkins KM, Zheng W, Cuddeback S, Yamada M, Lieberman HB, Wang HG. Human homologue of S. pombe rad9 interacts with BCL-2/BCL-x L and promotes apoptosis. Nat. Cell Biol. 2:1-6, 2000.   

  H. Hang, Rauth S.J., Hopkins K.M., Lieberman H.B. Mutant alleles of Schizosaccharomyces pombe rad9(+) alter hydroxyurea resistance, radioresistance and checkpoint control. Nucleic Acids Res. 28:4340-9, 2000.   

  1998年   

  H. Hang, S.J. Rauth, K.M. Hopkins, S.K. Davey. and H.B. Lieberman, Molecular cloning and tissue-specific expression of a murine orthologue of the Schizosaccharomyces pombe rad9 checkpoint control gene. J Cell Physiol. 177:241-7, 1998.   

  1996年   

  H. Hang and M.H. Fox. Levels of 70-kDa heat shock protein through the cell cycle in several mammalian cell lines. Cytometry. 25:367-373, 1996.   

  H. Hang, DN. Hager, L. Goriparthi, KM. Hopkins, H. Shih and HB. Lieberman. Schizosaccharomyces pombe rad23 is allelic with swi10, a mating-type switching/ radioresistance gene that shares sequence homology with human and mouse ERCC1. Gene. 170:113-117, 1996.   

  1995年   

  H. Hang, L. He and M.H. Fox. Cell cycle variation of hsp70 levels in HeLa cells at 37o C and after a heat shock. Journal of Cellular Physiology. 165:367-75, 1995.   

  H. Hang, L. He and M.H. Fox. Expression of hsp70 induced in CHO cells by 45.0o C hyperthermia is cell cycle associated and DNA synthesis dependent. Cytometry. 19: 119-125, 1995.   

  1994年以前   

  H. Hang and M.H. Fox. Low pH suppresses synthesis of heat-shock proteins and thermotolerance, Radiation Research. 140:24-30, 1994.   

  E.D. Wieder, H. Hang and M.H. Fox. The measurement of intracellular pH using flow cytometry with carboxy-SNARF-1. Cytometry. 14:1-6, 1993.   

  H. Hang, B. Feng, Z. Zhang. Studies on relationship between Na,K-ATPase activity and sperm capacitation in Guinea pig, Science in China (series B). 33:1304-1310, 1990.   

  * Correspondence author.

  

           
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