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中科院青促会会员

张泓泰  博士 副研究员  

中国科学院青年创新促进会会员

研究方向:病原微生物学

电子邮件:hongtaizhang@aliyun.com

电       话:010-64888671

通讯地址:北京市朝阳区大屯路15号(100101)

英文版个人网页:http://english.ibp.cas.cn/faculty/index_18316.html?json=http://www.ibp.cas.cn/sourcedb_ibp_cas/cn/ibpexport/EN_zkyqchhy/202005/t20200519_5582917.json

 

简       历:

  2000.09 - 2007.07  沈阳农业大学,获学士、硕士学位

  2007.07 - 2009.09  中国科学院生物物理所,实习研究员

  2009.09 - 2014.05  中国科学院近代物理研究所,获博士学位

  2009.09 - 2014.12  中国科学院生物物理研究所,助理研究员

  2014.12 - 至今       中国科学院生物物理研究所,副研究员

获奖及荣誉:

 

社会任职:

 

研究方向:

  主要从事结核病领域研究。从结核分枝杆菌、宿主(人、鼠)两方面研究,同时利用基因组、转录组和蛋白质组、代谢组等技术手段,多角度综合性研究结核病发病和耐药机理,寻找结核病早期诊断的分子标示物,以便采取针对性的措施控制肺结核疫情。

承担项目情况:

 

代表论著:

  1. Hongtai Zhang, Zhaogang Sun, Wenjing Wei, Zhonghui Liu, Joy Fleming, Shuai Zhang, Nan Lin, Ming Wang, Maoshan Chen, Yuhui Xu, Jie Zhou, Chuanyou Li*, Lijun Bi* & Guangming Zhou* (2014) Identification of serum microRNA biomarkers for tuberculosis using RNA-seq. PLoS ONE 9(2): e88909. doi:10.1371/journal.pone.0088909

  2. Hongtai Zhang, Dongfang Li, Lili Zhao, Joy Fleming, Nan Lin, Ting Wang, Zhangyi Liu, Chuanyou Li, Nicholas Galwey, Jiaoyu Deng, Ying Zhou, Yuanfang Zhu, Yunrong Gao, Tong Wang, Shihua Wang, Yufen Huang, Ming Wang, Qiu Zhong,  Lin Zhou, Tao Chen, Jie Zhou, Ruifu Yang, Guofeng Zhu, Haiying Hang, Jia Zhang, Fabin Li, Kanglin Wan*, Jun Wang*, Xian-En Zhang*& Lijun Bi* (2013) Genome sequencing of 161 Mycobacterium tuberculosis isolates from China identifies genes and intergenic regions associated with drug resistance. Nature Genetics 45, 1255–1260 doi:10.1038/ng.2735.

  3. Qu Y, Bi L, Ji X, Deng Z, Zhang H, Yan Y, Wang M, Li A, Huang X, Yang R, Han Y* (2012) Identification by cDNA cloning of abundant sRNAs in a human-avirulent Yersinia pestis strain grown under five different growth conditions. Future Microbiology Vol.7, No.4, Pages 535-547, DOI 10.2217/fmb.12.13.

  4. Jinjun Wu, Zhiping Zhang, Lesley A. Mitchenall, Anthony Maxwell, Jiaoyu Deng, Hongtai Zhang, Ying Zhou, Yuan-yuan Chen, Da-Cheng Wang, Xian-En Zhang* and Lijun Bi* (2011) The dimer state of GyrB is an active form: implications for the initial complex assembly and processive strand passage. Nucleic Acids Research 39, doi:10.1093/nar/gkr553

 

(资料来源:张泓泰副研究员,2020-10-27)