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中科院青促会会员

陈培华(客座)  博士 副研究员  

中国科学院青年创新促进会会员
中科院生物物理所,脑与认知科学国家重点实验室

研究方向:神经生物学

电子邮件:chenpeihua@ibp.ac.cn

电       话:010-64880905

通讯地址:北京市朝阳区大屯路15号(100101)

英文版个人网页:http://english.ibp.cas.cn/faculty/index_18316.html?json=http://www.ibp.cas.cn/sourcedb_ibp_cas/cn/ibpexport/EN_zkyqchhy/202005/t20200519_5582903.json

 

简       历:

  2001 - 2005  电子科技大学生命科学与技术学院 生物医学工程专业 大学本科

  2005 - 2010  浙江大学生物医学工程与仪器科学学院 生物医学工程专业 博士

  2010 - 2014  中科院生物物理研究所 神经生物学 博士后

  2014 - 2019  中科院生物物理研究所 副研究员

获奖及荣誉:

  2005年  四川省优秀毕业生

  2009年  浙江大学竺可桢奖学金、优秀研究生一等奖

  2010年  浙江省优秀毕业生

社会任职:

 

研究方向:

  1. 突触囊泡释放的分子生物学机理

  2. 高精度在体神经突触囊泡信号检测技术和方法

承担项目情况:

 

代表论著:

  1. Zhang W, Chen P*#, Zhou L, et al. A biomimetic bioelectronic tongue: A switch for On- and Off- response of acid sensations. Biosens and Bioelectron. 2016, in press.

  (* co-first author and # co-corresponding author)

  2.Chen P, Wu J, Zhao J, et al. PKD2L1/PKD1L3 channel complex with an alkali-activated mechanism and calcium- dependent inactivation. Eur Biophys J. 2015, 44, 483-492

  3. Dai J, Chen P, Tian H, Sun J. Spontaneous Vesicle Release Is Not Tightly Coupled to Voltage-Gated Calcium Channel- Mediated Ca2+ Influx and Is Triggered by a Ca2+ Sensor Other Than Synaptotagmin-2 at the Juvenile Mice Calyx of Held Synapses. J. Neurosci. 2015, 35(26), 9632-9637.

  4.Chen P, Zhang W, Chen Pg, et al. A serotonin-sensitive sensor for investigation of taste cell-to-cell communication. Biosens and Bioelectron. 2011, 26, 3054-3058.

  5.Chen P, Wang B, Cheng G, Wang P. Taste receptor cell-based biosensor for taste specific recognition based on temporal firing. Biosens and Bioelectron. 2009, 2515, 228-233.

  6.Chen P, Liu X, Wang B, et al. A biomimetic taste receptor cell-based biosensor for electrophysiology recording and acidic sensation. Sensor Actuat B-Chem. 2009, 139 (2), 576-583.

  7.Chen P, Zhang W, Zhou J, et al. Development of planar patch clamp technology and its application in the analysis of cellular electrophysiology. Prog Nat Sci. 2009, 19 (2), 153-160.

  8.Chen P, Liu X, Zhang W, et al. Modeling and simulation of ion channels and action potentials in taste receptor cells. Sci. China Ser. C, 2009, 52(11):1036-1047.

  9.Chen P, Cheng G, Wang B, et al. Design of a novel acid-sensing biosensor based on taste neurons and LAPS, The 2nd Bioinformatics and Biomedical Engineering, 2008.

  10.Wu C, Chen P, Yu H, et al. A novel biomimetic olfactory-based biosensor for single olfactory sensory neuron monitoring. Biosens and Bioelectron. 2009, 24(15), 1498-1502.

  11.Wu C, Chen P, Yuan Q, Wang P. Response enhancement of olfactory sensory neurons -based biosensors for odorant detection. J. Zhejiang Univ Sci B, 2009, 10 (4), 285-290.

参编专著:

  1.英文专著 《Cell-based Biosensors: Principles and Applications》Artech House Press, USA, 2009 (第七章)

  2.中文专著《细胞传感器原理及其应用》,王平 著,北京:科学出版社,2007 (第八章)

发明专利:

  1. 陈培华,孙坚原,申雪峰,戴金叶,张树利。“单个囊泡融合和回收及其与钙离子通道耦合的膜片钳检测装置”(专利申请号:201510104564.4)

  2. 陈培华,孙坚原,申雪峰。“膜片钳低噪温控装置” (专利申请号:201610676947.3)

  3. 申雪峰,孙坚原,陈培华。“具有高空间分辨率的亚微米/纳米碳纤电极”(专利申请号:201610680442.4)

  4. 申雪峰,孙坚原,陈培华,张树利。“适用于膜片钳电化学技术系统的新型碳纤电极”(专利申请号:201510104447.8)

  5. 戴金叶,孙坚原,陈培华,张树利。“微小单突触神经元的电活动记录方法”(专利申请号:201510657463.X)

 

(资料来源:陈培华副研究员,2019-11-21)