Angewandte Chemie International Edition，2012 Nov 29，DOI: 10.1002/anie.201207229 and 10.1002/ange.201207229
Probing the Function of the Tyr-Cys Crosslink in Metalloenzymes through the Genetic Incorporation of 3-Methylthiotyrosine
Qing Zhou+, Meirong Hu+, Wei Zhang+, Li Jiang, Sarah Perrett, Juanzuo Zhou, Jiangyun Wang*
Correspondence Author: Jiangyun Wang
Efficient multiple-electron redox reactions are performed by galactoase oxidase,cysteine dioxygenase, sulfite reductase, and ytochrome c nitrite reductase. A post-translationally modified tyrosine–cysteine cross-link (Tyr-Cys) in their active sites is essential for their functions.