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Probing the Function of the Tyr-Cys Crosslink in Metalloenzymes through the Genetic Incorporation of 3-Methylthiotyrosine,ANGEW CHEM INT EDIT ,2012 Nov 29

发布时间:2012年11月30日

Angewandte Chemie International Edition,2012 Nov 29,DOI: 10.1002/anie.201207229 and 10.1002/ange.201207229

Probing the Function of the Tyr-Cys Crosslink in Metalloenzymes through the Genetic Incorporation of 3-Methylthiotyrosine

Qing Zhou+, Meirong Hu+, Wei Zhang+, Li Jiang, Sarah Perrett, Juanzuo Zhou, Jiangyun Wang*

Correspondence Author: Jiangyun Wang

Abstract

Efficient multiple-electron redox reactions are performed by galactoase oxidase,cysteine dioxygenase, sulfite reductase, and ytochrome c nitrite reductase. A post-translationally modified tyrosine–cysteine cross-link (Tyr-Cys) in their active sites is essential for their functions.

相关报道:http://www.ibp.cas.cn/kyjz/zxdt/201211/t20121130_3694988.html

全文链接:http://dx.doi.org/10.1002/anie.201207229

http://dx.doi.org/10.1002/ange.201207229

 

 

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