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高利增课题组

陈雷助理研究员

中国科学院生物物理研究所
蛋白质与多肽药物重点实验室

研究方向：纳米酶催化机理的量子计算与研究

电子邮件：chenlei@ibp.ac.cn

电话：010-64888580

通讯地址：北京市朝阳区大屯路15号

英文版个人网页：

简历：

　1997-2001 吉林大学物理学院，本科

　2001-2004 吉林大学物理学院，硕士

　2004-2007 北京无线电测量研究所，工程师

　2009-2018 吉林大学，工程师/高级工程师

　2010-2014 吉林大学生命科学学院，博士

　2012-2013 香港城市大学，访问学者

　2017-2018 香港城市大学，高级访问学者

　2018-2020 扬州大学医学院，副教授

　2020-至今中国科学院生物物理研究所，助理研究员

获奖及荣誉：

社会任职：

研究方向：

　（1）纳米酶催化机理的量子计算与研究。

　（2）铁硫/铁氧纳米材料以及过渡金属配合物的研发和杀菌机制研究。

承担项目情况：

代表论著：

　1.Xiangqin Meng#, Dandan Li#, Lei Chen, Helen He, Qian Wang, Chaoyi Hong, Jiuyang He, Xingfa Gao, Yili Yang, Bing Jiang, Guohui Nie*, Xiyun Yan*, Lizeng Gao*, and Kelong Fan*, High-Performance Self-Cascade Pyrite Nanozymes for Apoptosis–Ferroptosis Synergistic Tumor Therapy. ACS Nano 2021, 15, 3, 5735-5751.

　2.Xinyu Shen#, Ruonan Ma#, Yixin Huang#, Lei Chen#, Zhuobin Xu, Dandan Li, Xiangqin Meng, Kelong Fan, Juqun Xi, Xiyun Yan, Hyun Koo, Yili Yang, Jing Jiang, Lizeng Gao*, Nano-decocted ferrous polysulfide coordinates ferroptosis-like death in bacteria for anti-infection therapy, Nano Today 35 (2020) 100981.

　3.Lei Chen, Fei Qi, Kulpavee Jitapunkul, Yan-Ling Zhao, Rui-Qin Zhang*, and Michel A. Van Hove*, An Intramolecular Torque Study of a Molecular Rotation Stimulated by Electron Injection and Extraction, J. Phys. Chem. A, 2018, 122 (38), 7614-7619.

　4.Lei Chen, Zhigang Wang*, Zhengqiang Li*, Rui-qing Zhang*, Chemical Coupling SERS Properties of Pyridine on Silver-Caged Metal Clusters M@Ag12 (M=V, Nb, Ta, Cr, Mo, W, Mn+, Tc+, Re+), Journal of ELECTRONIC MATERIALS, 2017，46，3904-3909.

　5.Yanbin Su#, Lei Chen#, Yanwen Su, Zhengqiang Li*, Chuang Zhang, Tongxing Mu, Spectroscopic evidences of toxic trans-crotonaldehyde trapped and transformed by resveratrol to prevent the damage of mitochondrial DNA. IUBMB life 2017, 69 (7), 500-509.

　6.Lei Chen, Yang Gao, Yingkun Cheng, Haichao Li, Zhigang Wang,* Zhengqiang Li*, Rui-Qin Zhang*, Nonresonant Chemical Mechanism in Surface-Enhanced Raman Scattering of Pyridine on M@Au12 Clusters. Nanoscale, 2016, 8, 4086-4093.

　7.Lei Chen, Yang Gao, Yingkun Cheng, Yanbin Su, Zhigang Wang,* Zhengqiang Li,* and Rui-Qin Zhang,* Strong Core@Shell Dependence in SERS of Pyridine on Stable 13-Atom Silver-Caged Bimetallic Clusters. J. Phys. Chem. C 2015, 119, 17429-17437.

　8.Yanbin Su#, Lei Chen#, Yingkun Cheng, Fengrong Zhang, Yanwen Su and Zhengqiang Li*, Raman spectroscopic characteristics of diallyl trisulfide acting on trans-crotonaldehyde. J. Raman Spectrosc. 2015, 46, 1067-1072.

　9.Yang Gao, Lei Chen, Xing Dai, Ruixia Song, Bo Wang and Zhigang Wang.* A Strong Charge-Transfer Effect in Surface-Enhanced Raman Scattering Induced by Valence Electrons of Actinide Elements. RSC Adv. 2015, 5, 32198-32204.

　10.Lei Chen, Yang Gao, Haoran Xu, Zhigang Wang*, Zhengqiang Li*, Rui-Qin Zhang*, The mechanism of N-Ag bonding determined tunability of surface-enhanced Raman scattering of pyridine on MAg (M = Cu, Ag, Au) diatomic clusters. Phys. Chem. Chem. Phys. 2014, 16 (38), 20665-20671.

　11.Lei Chen, Zhengqiang Li, Yan Meng, Ming Lu, Zhigang Wang*, and Rui-Qin Zhang*, Chemical Mechanism and Tunability of Surface-Enhanced Raman Scattering of Pyridine on Heteronuclear Coinage Metal Diatomic Clusters: A Density Functional Study. J. Phys. Chem. C 2013, 117(24), 12544-12551.