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发展中国家科学院院士

王志新  院士 研究员 博士生导师  

中国科学院院士,第三世界科学院院士  
国家“杰出青年基金”获得者
中科院生物物理所,生物大分子国家重点实验室,研究组长

研究方向:蛋白质物理化学、酶活性调节动力学、蛋白-配体相互作用、蛋白质结构预测

电子邮件:zxwang@ibp.ac.cn/zhixinwang@mail.tsinghua.edu.cn

电       话:010-64889890

通讯地址:北京市朝阳区大屯路15号(100101)

英文版个人网页:http://english.ibp.cas.cn/faculty/index_18316.html?json=http://www.ibp.cas.cn/sourcedb_ibp_cas/cn/ibpexport/EN_zgkxyys/202005/t20200519_5583035.json

 

简       历:

  1988        中国科学院生物物理研究所获博士学位。

  1989 - 1993 在美国康乃尔大学和北达科他州立大学从事博士后研究。

  1993        回国任生物物理研究所研究员至今。

  1997        当选为中国科学院院士。

  现任清华大学生物科学与技术系教授。任中国生物物理学会常务理事,北京市生物化学学会副理事长,《中国科学》杂志编委,北京市学位委员会委员,第九届全国政协委员。

获奖及荣誉:

 

社会任职:

 

研究方向:

  主要研究蛋白质物理化学、酶活性调节动力学、蛋白-配体相互作用、蛋白质结构预测。在SCI收录的期刊发表论文70篇。

承担项目情况:

 

代表论著:

  1. Li-Sha Zheng, Yuan-Yuan Zhang, Jia-Wei Wu, Zhenguo Wu, Zhong-Yin Zhang, Zhi-Xin Wang, A continuous spectrophotometric assay for mitogen-activated protein kinase kinases, Anal. Biochem. 2012 421 191-197

  2. Hongwei Yao, Yingang Feng, Tao Zhou, Jinfeng Wang, Zhi-Xin Wang, NMR Studies of the Interaction between Human Programmed Cell Death 5 and Human p53, Biochemistry 2012 51 2684-2693

  3. Tian Xie, Ruobing Ren, Yuan-yuan Zhang, Yuxuan Pang, Chuangye Yan, Xinqi Gong, Yuan He, Wenqi Li, Di Miao, Qi Hao, Haiteng Deng, Zhixin Wang, Jia-Wei Wu, Nieng Yan, Molecular Mechanism for Inhibition of a Critical Component in the Arabidopsis thaliana Abscisic Acid Signal Transduction Pathways, SnRK2.6, by Protein Phosphatase ABI1, J. Biol. Chem. 2012 287 794-802

  4. Yuan-Yuan Zhang, Jia-Wei Wu, Zhi-Xin Wang, Mitogen-activated Protein Kinase (MAPK) Phosphatase 3-mediated Cross-talk between MAPKs ERK2 and p38, J. Biol. Chem. 2011 286

  5. Jue Wang, Jia-Wei Wu, Zhi-Xin Wang, Mechanistic Studies of the Autoactivation of PAK2, A TWO-STEP MODEL OF CIS INITIATION FOLLOWED BY TRANS AMPLIFICATION, J. Biol. Chem. 2011 286 2689-2695

  6. Yi-Tong Liu, Qiong-Jie Dan, Jiawei Wang, Yingang Feng, Lei Chen, Juan Liang, Qinxi Li, Sheng-Cai Lin, Zhi-Xin Wang, Jia-Wei Wu, Molecular Basis of Wnt Activation via the DIX Domain Protein Ccd1, J. Biol. Chem. 2011 286 8597-8608

  7. Yuan-Yuan Zhang, Jia-Wei Wu, Zhi-Xin Wang, A Distinct Interaction Mode Revealed by the Crystal Structure of the Kinase p38a with the MAPK Binding Domain of the Phosphatase MKP5, Sci. Signal. 2011 4

  8. Jue Wang, Jia-Wei Wu, Zhi-Xin Wang, Structural Insights into the Autoactivation Mechanism of p21-Activated Protein Kinase , Structure 2011 19 1752-1761

  9. Lei Chen, Zhi-Hao Jiao, Li-Sha Zheng, Yuan-Yuan Zhang, Shu-Tao Xie, Zhi-Xin Wang, Jia-Wei Wu1, Structural insight into the autoinhibition mechanism of AMP-activated protein kinase, Nature 2009 459 1146-U139

  10. Rui Hao,a Lei Chen,b Jia-Wei Wub,Zhi-Xin Wang, Structure of Drosophila Mad MH2 domain, Acta Crystallogr. F- 2008 64 986-990

  

(资料来源:王志新院士,2014-09-01)