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百千万人才工程入选者

刘力博士研究员博士生导师

国家“杰出青年基金”获得者
中科院生物物理研究所党委书记、副所长
脑与认知科学国家重点实验室研究组长
中国科学院大学生命科学学院教授

研究方向：视觉信息处理及学习记忆等认知行为的细胞分子机制

电子邮件：liuli@ibp.ac.cn

电话：010-64888550

通讯地址：北京市朝阳区大屯路15号（100101）

英文版个人网页：http://english.ibp.cas.cn/faculty/index_18316.html?json=http://www.ibp.cas.cn/sourcedb_ibp_cas/cn/ibpexport/EN_xsszmL/202005/t20200519_5582994.json

简历：

　　1985 - 1989 南开大学物理系，获理学学士学位

　　1989 - 1991 南开大学，工作

　　1991 - 1996 中国科学院生物物理研究所，获理学博士学位

　　1996 - 1997 中国科学院生物物理研究所，助理研究员

　　1997 - 1999 德国维尔兹堡大学，博士后

　　1999 - 至今中国科学院生物物理研究所，研究员

　　2014 - 至今中国科学院大学生命科学学院，教授

获奖及荣誉：

社会任职：

研究方向：

　　在“基因、脑和行为”的框架下，以果蝇为模型，采用分子遗传学、细胞生物学、神经电生理以及行为学相结合的方法，主要研究视觉信息处理以及学习记忆等认知行为的神经回路及细胞分子机制:（1）视觉学习记忆的神经回路及细胞分子机制；（2）视觉信息处理的神经机制；（3）神经系统中长非编码RNA的功能机制。

研究团队/课题组成员：

	李美霞博士，副研究员 limeixia@ibp.ac.cn		魏虹莹博士，副研究员 weihongying@ibp.ac.cn
	许孟博博士，高级工程师 xmb@ibp.ac.cn		段文兰，博士研究生 wenlan_duan@hotmail.com
	崔名扬，博士研究生 cmybjfu13@163.com		张艺豪，硕士研究生 yhz1610alan@163.com
	张鑫，硕士研究生 18717707298@163.com		王应璇，硕士研究生 1119089944@qq.com

承担项目情况：

代表论著：

1. Deliang Yuan, Xiaoxiao Ji, Shun Hao, Julia Yvonne Gestrich, Wenlan Duan, Xinwei Wang, Yuanhang Xiang, Jihua Yang, Pengbo Hu, Mengbo Xu, Li Liu, Hongying Wei (2021) Lamina feedback neurons regulate the bandpass property of the flicker-induced orientation response in Drosophila. Journal of Neurochemestry, 156:59–75.

2. Xiaoxiao Ji, Deliang Yuan, Hongying Wei, Yaxin Cheng, Xinwei Wang, Jihua Yang, Pengbo Hu, Julia Yvonne Gestrich, Li Liu, Yan Zhu (2020) Differentiation of theta visual motion from Fourier motion requires LC16 and R18C12 neurons in Drosophila. iScience, 23:101041.

3. Mengbo Xu, Yuanhang Xiang, Xiaojun Liu, Baoyan Bai, Runsheng Chen, Li Liu, Meixia Li (2019) Long noncoding RNA SMRG regulates Drosophila macrochaetes by antagonizing scute through E(spl)mβ. RNA Biology, 16:42-53.

4. Qionglin Peng, Yijin Wang, Meixia Li, DeliangYuan, Mengbo Xu, Changqing Li, Zhefeng Gong, Renjie Jiao, Li Liu (2016) cGMP-dependent protein kinase encoded by foraging regulates motor axon guidance in Drosophila by suppressing Lola function. The Journal of Neuroscience, 36(16):4635-4646.

5. Chao Guo, Yifei Du, Deliang Yuan, Meixia Li, Haiyun Gong, Zhefeng Gong, Li Liu (2014) A conditioned visual orientation requires the ellipsoid body in Drosophila. Learning & Memory, 22:56-63.

6. Jiangqu Liu, Zhefeng Gong, Li Liu (2014) γ-glutamyl transpeptidase 1 specifically suppresses green-light avoidance via GABAA receptors in Drosophila. Journal of Neurochemestry, 130:408-418.

7. Xuebo Cheng, Huoqing Jiang, Weizhe Li, Hailong Lv, Zhefeng Gong, Li Liu (2013) ten-a affects the fusion of central complex primordia in Drosophila. PLOS One, 8 (2):e57129.

8. Meixia Li, Shengyun Wen, Xiangqian Guo, Baoyan Bai, Zhefeng Gong, Xiaojun Liu, Yijin Wang, Yanqiong Zhou, Xiaowei Chen, Li Liu, Runsheng Chen (2012) The novel long non-coding RNA CRG regulates Drosophila locomotor behaviour. Nucleic Acids Research, 40(22):11714-11727.

9. Yanqiong Zhou, Xiaoxiao Ji, Haiyun Gong, Zhefeng Gong, Li Liu (2012) Edge detection depends on achromatic channel in Drosophila melanogaster. Journal of Experimental Biology, 215:3478-3487.

10. Huoqing Jiang, Qinlong Hou, Zhefeng Gong, Li Liu (2011) Proteomic and transcriptomic analysis of visual long-term memory in Drosophila melanogaster. Protein & Cell, 2(3):215-222.

11. Zhefeng Gong, Jianqu Liu, Chao Guo, Yanqiong Zhou, Yan Teng, Li Liu (2010) Two pairs of neurons in central brain control Drosophila innate light preference. Science, 330:499-502.

12. Yan Xiong, Hailong Lv, Zhefeng Gong, Li Liu (2010) Fixation and locomotor activity are impaired by inducing tetanus toxin expression in adult Drosophila brain. Fly, 3 (4):194-203.

13. Weizhe Li, Yufeng Pan, Zhipeng Wang, Haiyun Gong, Zhefeng Gong, Li Liu (2009) Morphological characterization of single fan-shaped body neurons in Drosophila melanogaster. Cell Tissue Research, 336:509-519.

14. Yufeng Pan, Yanqiong Zhou, Chao Guo, Haiyun Gong, Zhefeng Gong, Li Liu (2009) Differential roles of the fan-shaped body and the ellipsoid body in Drosophila visual pattern memory. Learning & Memory, 16:289-295.

15. Zhipeng Wang, Yufeng Pan, Weizhe Li, Huoqing Jiang, Lazaros Chatzimanolis, Jianhong Chang, Zhefeng Gong, Li Liu (2008) Visual pattern memory requires foraging function in the central complex of Drosophila. Learning & Memory, 15:133-142.

16. Gang Liu, Holger Seiler, Ai Wen, Troy Zars, Kei Ito, Reinhard Wolf, Martin Heisenberg, Li Liu (2006) Distinct memory traces for two visual features in the Drosophila brain. Nature, 439:551-556.

17. Li Liu, Reinhard Wolf, Roman Ernst, Martin Heisenberg (1999) Context generalization in Drosophila visual learning requires the mushroom bodies. Nature, 400:753-756.

（资料来源：刘力研究员，2022-01-04）