代表论著

1. Xue, F., Yuan, L.*, He, W., ... & Xu, P.* (2026). High-fidelity single-frame computational super-resolution using signal-preserving denoising-enabled deconvolution. Nature Communications, Accepted.

2. Ding, Y., He, W., Wang, K., Xue, F., Zheng, K., Zhao, S., ... Yuan, L.* & Xu, P.* (2025). A highly photostable monomeric red fluorescent protein for dual-color 3D STED and time-lapse 3D SIM imaging. Nature Methods, 23, 143-152.

3. Wang, Z., Hu, F., Xue, F., He, W., Yuan, L.*, & Xu, P.* (2025). ALFA nanobody-guided endogenous labeling. Nature Chemical Biology, 21(12), 1992-2001.

4. Chen, Z., Jiang, H., Yuan, L., Yao, T., Rong, X., Gao, W., ... Zhang, J. *, Xu, P.* & Li, X.* (2025). Photoactivatable RNA Tags for Subcellular Photolabeling of RNA. Journal of the American Chemical Society, 147(35), 31650-31661.

5. Xue F, He W, Peng D, Hui You, Zhang, M*, Xu, P.* (2025). SOGO-SOFI, light-modulated super-resolution optical fluctuation imaging using only 20 raw frames for high-fidelity reconstruction. Fundamental Research, 5, 1025-1023

6. Pei X, Wang Z, He W, ...Lin Y.* & Xu P*. ER-tethered RNA-binding protein controls NADPH oxidase translation for hydrogen peroxide homeostasis. Redox Biology, 2024, 71: 103126.

7. Liu, A., Huang, X., He, W., Xue, F., Yang, Y., Liu, J., ...Lin Y.* & Xu P*. (2021). pHmScarlet is a pH-sensitive red fluorescent protein to monitor exocytosis docking and fusion steps. Nature Communications, 12(1), 1-12.

8. Fu, Z., Peng, D., Zhang, M., …& Xu, T.*, Xu, P.* (2020). mEosEM withstands osmium staining and Epon embedding for super-resolution CLEM. Nature methods, 17(1), 55-58.

9. Zhang, M., Fu, Z., Li, C., Liu, A., Peng, D., Xue, F., ... & Xu, T.*, Xu, P.* (2020). Fast super-resolution imaging technique and immediate early nanostructure capturing by a photoconvertible fluorescent protein. Nano letters, 20(4), 2197-2208. (Cover)

10. Peng D, Li N, He W, ...Xu, P.*. Improved fluorescent proteins for dual-colour post-embedding CLEM. Cells, 2022, 11(7): 1077.

11. Pei X, Wang H, Xu P, et al. The core autophagy protein ATG5 controls the polarity of the Golgi apparatus and insulin secretion of pancreatic beta cells. Biochemical and Biophysical Research Communications, 2022, 629: 26-33.

12. Yuan, L., Liu, Q., Wang, Z., Hou, J., & Xu, P*. (2019). EI24 tethers endoplasmic reticulum and mitochondria to regulate autophagy flux. Cellular and Molecular Life Sciences, 2019 Jul 22. doi: 10.1007/s00018-019-03236-9.

13. Yuan, L., Wang, H., Liu, Q., Wang, Z., Zhang, M., Zhao, Y., ... & Xu, T.*, Xu, P.* (2018). Etoposide-induced protein 2.4 functions as a regulator of the calcium ATPase and protects pancreatic β-cell survival. Journal of Biological Chemistry, 293(26), 10128-10140.

14. Xu, F., Zhang, M., He, W., Han, R., Xue, F., Liu, Z., Zhang, F.*, Lippincott-Schwartz, J.*, Xu, P.* (2017). Live cell single molecule-guided Bayesian localization super resolution microscopy. Cell research, 27(5), 713.

15. Zhang, X., Zhang, M., Li, D., He, W., Peng, J., Betzig, E.*, & Xu, P*. (2016). Highly photostable, reversibly photoswitchable fluorescent protein with high contrast ratio for live-cell superresolution microscopy. Proceedings of the National Academy of Sciences, 113(37), 10364-10369.

16. Du, W., Zhou, M., Zhao, W., Cheng, D., Wang, L., Lu, J., ... & Xue, Y.H.*, Xu, P.*, Xu, T.*(2016). HID-1 is required for homotypic fusion of immature secretory granules during maturation. Elife, 5, e18134.

17. Zhang, X., Chen, X., Zeng, Z., Zhang, M., Sun, Y., Xi, P.*, Peng, J.*, Xu, P.* (2015). Development of a reversibly switchable fluorescent protein for super-resolution optical fluctuation imaging (SOFI). ACS nano, 9(3), 2659-2667.

18. Chen, J. J., Jing, J., Chang, H., Rong, Y., Hai, Y., Tang, J., Zhang, J.*, Xu, P.* (2013). A sensitive and quantitative autolysosome probe for detecting autophagic activity in live and prestained fixed cells. Autophagy, 9(6), 894-904.

19. Jing, J., Chen, J. J., Hai, Y., Zhan, J., Xu, P.*, & Zhang, J. L.* (2012). Rational design of ZnSalen as a single and two photon activatable fluorophore in living cells. Chemical Science, 3(11), 3315-3320.

20. Zhang, M., Chang, H., Zhang, Y., Yu, J., Wu, L., Ji, W., ... & Zhang, J., Xu, P.*, Xu, T.* (2012). Rational design of true monomeric and bright photoactivatable fluorescent proteins. Nature methods, 9(7), 727.

21. Chang, H., Zhang, M., Ji, W., Chen, J., Zhang, Y., Liu, B., ... & Xu, P.*, Xu, T.* (2012). A unique series of reversibly switchable fluorescent proteins with beneficial properties for various applications. Proceedings of the National Academy of Sciences, 109(12), 4455-4460.

22. Hai, Y., Chen, J. J., Zhao, P., Lv, H., Yu, Y., Xu, P.*, Zhang, J. L.* (2011). Luminescent zinc salen complexes as single and two-photon fluorescence subcellular imaging probes. Chemical Communications, 47(8), 2435-2437.　

23. Ji, W., Xu, P., Li, Z., Lu, J., Liu, L., Zhan, Y., Hille, B.*, Xu, T.*, Chen L. *(2008). Functional stoichiometry of the unitary calcium-release-activated calcium channel. Proceedings of the National Academy of Sciences, 105(36), 13668-13673. (Pingyong Xu as co-first author)

24. Bai, L., Wang, Y., Fan, J., Chen, Y., Ji, W., Qu, A., Xu, P.*, James, D.E., Xu, T. (2007). Dissecting multiple steps of GLUT4 trafficking and identifying the sites of insulin action. Cell metabolism, 5(1), 47-57.

专  利

1. 徐平勇，张法，徐帆，张名姝，贺文婷。一种贝叶斯显微成像方法。（专利号：ZL201610282305.5）

2. 徐平勇，徐涛，张名姝，付志飞，彭鼎铭。一种光控荧光蛋白。（专利号：ZL201910486631.1）

3. 徐平勇，袁琳，贺文婷，薛福东。基于光开关分子的去噪去卷积超分辨成像方法和装置（申请号：202311839967.4）

4. 徐平勇，袁琳，贺文婷，薛福东。基于深度学习去噪的去卷积超分辨成像方法、装置及介质（申请号：202311839953.2）

5. 徐平勇，丁姝瑶，毛珩，杨润甲，贺文婷。一种超分辨成像方法、装置及设备。（申请号：202411482206.2）

6. 徐平勇，徐涛，刘成，贺文婷，袁琳。一种干片荧光成像样品的制备方法及成像方法。（申请号：202510909931.1）

7. 徐平勇，徐涛，刘成，袁琳，贺文婷。一种用于干片成像的红色荧光探针及应用。（申请号：202511294868.1）

8. 徐平勇，徐涛，刘成，袁琳，贺文婷。 一种用于干片成像的绿色荧光探针及应用。（申请号：202511532838.X）

9. 梁晨，杨宏润，丰帆，徐平勇，贺文婷。一种用于荧光蛋白筛选的自动化成像装置和方法（申请号：202411104252.9）

10. 梁晨，丰帆，徐平勇，贺文婷。适用于深层组织样本成像的多模态显微成像系统及方法（申请号：202410709063.8）

（资料来源：徐平勇研究员，2026-03-09）