Significance : Severe acute respiratory syndrome coronavirus 2 ( SARS-CoV-2 ) is a severe threat to public health and the global economy .Our study presents the in situ structure of the spike protein in the postfusion state with higher resolution , giving further insights into the design of a viral e...
Structures of human mGlu2 and mGlu7 homo- and heterodimers
Cryo-electron tomography ( cryo-ET ) provides a promising approach to study intact structures of macromolecules in situ , but the efficient preparation of high-quality cryosections represents a bottleneck .Two strategies were developed for loading cryo-lamella via a side-entry cryo-holder or an FEI A...
